Today’s AI Top Pick: ALNY

8/4/2026 · Contrarian screen · a free sample of K3vl4r’s AI-curated picks.

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Today's pick · ContrarianALNYBUY NOW8.4 / 108/4/2026

Alnylam Pharmaceuticals is the cleanest contrarian bounce setup in the pool. Fundamentals are best-in-class among the candidates (fundamental_score 8, the highest): ROE 100.7%, salesYoY +95.14%, profitMargin 16.82%, PEG 0.29, fwdPe 22.3, recom 1.6, targetUpsidePct 74.1%. Unlike the majority of the pool, ALNY is a profitable, growing large-cap ($29.5B) selling off inside an earnings/guidance-adjustment window, not a broken small-cap. Multi-timeframe forecasts are strongly aligned on the short and intermediate horizons: 1h fc_short/mid/long = +39.06/+38.19/+39.30%, 4h = +39.27/+44.87/+73.44%, 1d = +2.73/+66.25/+58.16%. Only the 1wk is soft (-8.82/-6.74/+1.14), which is a mild caution but consistent with a base-building phase rather than a v-shaped melt-up. Position in the 21-bar range is very low across all TFs (14.74% 1h, 2.92% 4h, 13.4% 1d, 13.53% 1wk) with drawdowns of -26% to -33% — this is exactly the profile the strategy wants: deep drawdown, price sitting near the low, but forecasts inflecting up. The news check is favorable. The Q2 2026 call just released (Aug 4), Barclays reiterated Overweight (only trimming PT to $450 — still huge upside from $221.30), and ChartMill published a growth-at-reasonable-value piece. There is no guidance cut, no dilution, no legal overhang — a rare clean slate versus MYGN (cut 2026 revenue outlook), LII (cut 2026 EPS), LEGN (CEO exit), ALHC (downgrade), EVH (Citi downgrade + StockStory 'nosediving'), and TDOC (guidance pressure). ALNY's bullish_prob is 1.0 and forecast magnitudes are strong without being cartoonish, which fits a genuine mean-reversion rather than a lottery-ticket bounce. Why today: at $221.30 with pos_in_range ~2-14% across TFs, you are buying near the 21-bar low, not chasing. RSI 31.28 confirms oversold. The event risk (Q2 print) is now behind us, and analyst PTs are being trimmed to still-bullish levels rather than slashed — that is 'exhausted selling' behavior. Waiting for a weekly turn risks missing the initial +25-40% snap that the 1h/4h/1d models are projecting.

ALNY forecast chart
Entry zone
$215 - $228 (scale in around current $221.30; add on any test of $210-215 support)
Stop loss
$193 (below the 21-bar low structure; ~13% risk from mid-entry)
First target
$262 - $275 (fills gap and matches short-horizon +18-25% forecast alignment)
Longer target
$330 - $385 (aligns with 4h fc_long +73% and analyst targetUpsidePct 74.1% / Barclays $450 PT)
Risks
  • Weekly forecasts are negative (fc_short -8.82%, fc_mid -6.74%) — longer-term trend not yet confirmed; bounce may fade at $260-280 resistance
  • Barclays and other sell-side firms cut price targets on Aug 3-4 even while maintaining bullish ratings — sentiment reset ongoing, could pressure shares near-term
  • Debt/Equity 2.21 is elevated for a biotech; rate/credit shocks could weigh disproportionately
  • perfYear -45.16% and perfYtd -44.59% show this is a downtrending name — a failed bounce would re-open $180s downside (-18%)
  • PE 37.2 is not cheap on trailing; thesis leans on epsNextY +45.77% actually landing
Honorable mentions
NAUTExtreme oversold (RSI 21.97, drawdown -40.6%, pos_in_range 4-13%) with monster multi-TF forecasts (1h +108/+125/+127%, 4h +117/+124/+124%, 1wk +20/+105/+180%) and a fresh positive contrarian SeekingAlpha piece post Q2. Fundamentals are ugly (profitMargin -29,747%, PS 676) so size it small — pure signal/narrative bounce trade.
PHATBest combination of analyst support (recom 1.30, Guggenheim + HC Wainwright Buy reiterations post-earnings) with strong short-horizon forecasts across 1h/4h (+21-40% mid) and only a moderate -21% drawdown. epsNextY +219%, salesYoY +110%, targetUpsidePct 143.9%. Cleaner news backdrop than most healthcare names here.
Full ranking (30)
#SymbolVerdictScoreRead
1ALNYBUY NOW8.4Best fundamentals in pool (score 8), multi-TF forecasts +39 to +73%, low range position, clean post-earnings news backdrop.
2NAUTBUY NOW7.3Deeply oversold with the largest coherent multi-TF forecast stack in the pool and a fresh positive contrarian writeup.
3PHATBUY NOW7.1Post-earnings buy reiterations, epsNextY +219%, near-term forecasts up across 1h/4h/1d, moderate -21% drawdown.
4ADTNBUY NOW6.7Fundamental_score 5.75, PEG 0.18, fwdPe 11.4, 1h/4h forecasts +55-90%, pos_in_range near 0-5%; only worry is soft 1wk fc.
5ALHCBUY PULLBACK6.4Solid fundamentals (score 5.75) and 1h/4h/1d forecasts up +25-69%, but Raymond James downgrade Aug 3 argues for waiting a session or two.
6CMTGBUY NOW6.2Pos_in_range 0-2% across TFs, all TFs forecast up (+28 to +165% by 1wk long), post-Q2 earnings news benign.
7FIPBUY PULLBACK6.0Recom 1.0, salesYoY +72%, forecasts +38-63% across 1h/4h/1d; Q2 print Aug 4 is event risk.
8LEGNBUY PULLBACK5.81h/4h/1d/1wk all forecast up (+22-80% mid), but CEO exit last week is an unresolved overhang.
9EVHBUY PULLBACK5.6Massive weekly forecast (+269/+394%) and RSI 25, but Citi downgrade + PT cuts require price stabilization first.
10MNROBUY PULLBACK5.5All TFs align up (+27-50% mid/long), fundamentals modest, but Stephens PT cut and 'trading lower' headline just this week.
11INDPBUY PULLBACK5.4Huge weekly forecasts (+547-693%) and analyst targetUpside 663%, but micro-cap biotech with -931% ROE — size tiny.
12ACIBUY PULLBACK5.3CEO open-market buy $450k is a real positive; forecasts +25-59% but PE 153 and debtEq 9.74 cap enthusiasm.
13OXT-USDBUY PULLBACK5.0Crypto: 1wk forecasts +82/+178/+245%, but 1d already +208% recent — chasing risk on shorter TF.
14COW-USDBUY PULLBACK4.91d forecast +75/+94%, but 1h/4h at range floor — good setup, no near-term catalyst clarity.
15LIIWAIT4.7Fundamentals decent but Goldman PT cut post 2026 EPS guidance cut — bounce shallow (+3-25%) and top of range 99% on 1h.
16GRMLBUY PULLBACK4.5Insider CFO acquired 1.4M shares — real signal; 1d forecast +80-131%, but 1h pos_in_range 73% is already extended.
17TVRDWAIT4.3Big forecasts and BTIG Buy, but active ATM offering ($9.69M) means dilution overhang.
18FIDA-USDWAIT4.21d forecast +9/+35/+46%, moderate setup, no strong catalyst.
19TDOCWAIT4.0Guidance pressure articles Aug 3-4, forecasts modest (+15% best case long) — poor risk/reward vs peers.
20GXAIWAIT3.8Post-divestiture pivot narrative, forecasts +44-77% short/mid, but $8.77M cap and weak recent action.
21NXLWAIT3.61d fc_long +93.6% is nice, but 1wk fc_short -6% and 1h pos_in_range only 19% — no urgency and micro-cap thin.
22JTO-USDWAIT3.5Mixed signals: 1d fc negative, 1wk fc_mid -26%; recent 21bar +80% already.
23IO-USDWAIT3.31d fc negative (-8 to -10%); only 4h leg mildly bullish — not a coherent setup.
24AIFAWAIT3.01wk fc +404% looks like noise; profitMargin -457% and $10M cap — lottery only.
25MMAAVOID2.9$10M micro-cap, perfYear -62%, weekly fc negative — bounce is speculation on speculation.
26NIXXAVOID2.71h fc negative -9.86% across horizons — model does not confirm the bounce on shortest TF.
27MYGNAVOID2.5Cut 2026 revenue outlook and missed Q2 just days ago — falling knife with fundamental_score 0.
28PMECAVOID2.31wk forecasts negative (-8 to -28%), fundamental_score -2.5, $15M micro-cap — broken chart.
29METCAVOID2.2SeekingAlpha 'valuation too expensive' Jul 16, Goldman PT cut, negative earnings expected — thesis undercut.
30CLROAVOID1.8Fundamental_score -3.25, salesYoY -81%, targetUpside -4.5% — no coherent contrarian case.

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⚠️ This AI-generated analysis is for informational purposes only and is not financial advice. Forecasts and scores are model outputs that can be wrong; markets involve substantial risk of loss. Do your own research.